sclerosis
//skləˈroʊsɪs//
Noun
sclerosisSingular
sclerosesPlural
1
A pathological hardening or thickening of body tissue, especially of the nervous system or the walls of arteries.
Multiple sclerosis is a disease that affects the central nervous system.
2
A condition marked by the replacement of normal tissue with fibrous or hardened tissue, often resulting in loss of function.
The doctor explained that sclerosis of the liver can lead to serious complications.
3
(figurative) A state of rigidity, inflexibility, or resistance to change in an organization, system, or society.
The sclerosis of the bureaucracy has prevented any meaningful reform.